CRC 1450 - B06: Dynamic PET-MRI for integrated quantification of molecular immune responses and their vascular consequences
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2025 - 31/12/2028 | 2nd Funding period
Description
The aim of the project is to elaborate synergistic links across PET/MRI by dual dynamic recordings and pharmacokinetic modelling. A framework to deduce the PET arterial input function from MRI will be established by performing simultaneous recordings in animals, and finally tested in patient scans. Building on this, approaches will be evaluated to integrate MRI-derived information on perfusion and permeability into PET modelling in mouse models of ischemia driven inflammation in the heart and kidney to uncover and better understand unspecific radiotracer uptake phenomena.
Keywords: Positron emission tomography–magnetic resonance imaging; Magnetresonanztomographie; Positronen-Emissions-Tomographie
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-B/B06.php
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/452340105
Funding identifier: SFB 1450/2, B06
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Backhaus, Philipp | European Institute of Molecular Imaging (EIMI) |
| Büther, Florian | European Institute of Molecular Imaging (EIMI) |
Applicants from the University of Münster
| Backhaus, Philipp | European Institute of Molecular Imaging (EIMI) |
| Büther, Florian | European Institute of Molecular Imaging (EIMI) |
Research associates from the University of Münster
| Cufe, Juela | Clinic for Nuclear Medicine |
| Gierse, Florian Werner | European Institute of Molecular Imaging (EIMI) |