NHC catalyzed oxidations of aldehydes to esters: chemoselective acylation of alcohols in presence of amines.
De Sarkar S, Grimme S, Studer A
Research article (journal)Abstract
Not just one but two carbenes of the same structure act cooperatively in oxidative acylations of alcohols with aldehydes by using a readily available cheap organic oxidant. Alcohols are selectively acylated in the presence of amines by cooperative carbene catalysis. Quantum chemical calculations support the suggested mechanism.
Details about the publication
Journal: Journal of the American Chemical Society (J. Am. Chem. Soc.)
Volume: 132
Issue: 4
Page range: 1190-1
Status: Published
Release year: 2010 (03/02/2010)
DOI: 10.1021/ja910540j
Authors from the University of Münster
| Grimme, Stefan | Organic Chemistry Institute |
| Studer, Armido | Professur für Organische Chemie (Prof. Studer) |