CRC 858 A04 - Cooperative Asymmetric Catalysis with Heterobimetallic Systems (SFB 858)

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/01/2010 - 31/12/2013 | 1st Funding period

Description

Project A4 focuses on the development of novel catalytic heterobimetallic systems for asymmetric cooperative catalysis. BINOL derivatives are exploited as chiral building blocks. Ligand precursors shall be generated in a pseudo combinatorial "Click"-chemistry approach via Huisgen-[3+2]-cylcoaddition chemistry with BINOL-azides and/or -alkynes. Within the resulting multifunctional systems the specific choice of a metal center may allow the modulation of the catalyst's properties. Asymmetric aldol type reactions, addition reactions, hydrogenations of pyridines and hetero-Diels-Alder-reactions are envisaged as catalytic test transformations. Dual activation should provide an increase in reactivity and selectivity of the reaction substrates. In addition, the respective reference systems shall also be generated and tested in order to determine potential cooperative effects appearing.

Keywords: catalytic heterobimetallic systems; asymmetric cooperative catalysis; metal center; addition reaction; aldol type reaction; hydrogenation; pyridines; hetero-Diels-Alder-reaction

Website of the project: http://www.uni-muenster.de/SFB858/

Funding identifier: INST 211/506-1:1

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