CRC 1009 A10 - Regulation of blood-brain-barrier function by pericytes
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2016 - 30/06/2020 | 1st Funding period
Description
The function of the blood-brain barrier relies on close interactions between different cell types including endothelial cells, pericytes and astrocytes. Here, we propose to study the role of the transcriptional coactivators YAP/TAZ and the Hippo signaling pathway in brain pericytes with cell type-specific and inducible genetic approaches in mice, cell biology, RNA sequencing, and biochemistry experiments. The planned work will provide important novel insights into the functional properties of pericytes and their role in the regulation of the blood-brain barrier.
Keywords: Endothelial cell biology
Website of the project: https://campus.uni-muenster.de/de/sfb-1009/projekte/projektbereich-a/a-10/
Funding identifier: SFB 1009/2
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Adams, Ralf Heinrich | Max Planck Institute for Molecular Biomedicine |
Applicants from the University of Münster
| Adams, Ralf Heinrich | Max Planck Institute for Molecular Biomedicine |