Univ.-Prof. Dr. med. Luisa Hildegard Klotz
Current affiliations
- Department for Neurology
Curriculum Vitae (CV)
- Neuroimmunology
- Multiple sclerosis
- Immunemodulation by nuclear receptors
- Immunological effects of modern MS-therapy
- Endogenous control of CNS-autoimmunity
Academic Education | |
| 2010 | Habilitation in Neurology |
| 2002 | Doctoral thesis, Institute for pathology, University hospital Bonn; “Morphologische und Proliferationskinetische Veränderungen von Hepatozyten im Abstromgebiet von Ovar- und Schilddrüsentransplantaten“ (grade: „summa cum laude“) |
| 1994 - 2001 | MD, University of Bonn, Medical School (degree 1.2) |
Work Experience | |
| since 2020 | Prodekanin für Forschung und wissenschaftlichen Nachwuchs der Medizinischen Fakultät Münster |
| since 2020 | Vertreterin des Dekans der Medizinischen Fakultät Münster |
| since 11/2016 | W3 Stiftungsprofessur für neurologische Immuntherapie und Oberärztin an der Klinik für Neurologie mit Institut für Translationale Neurologie, Universitätsklinik Münster (Direktor: Univ.-Prof. Prof. h. c. Dr. med. H. Wiendl) |
| since 06/2013 | Leiterin des Studienzentrums Neuroimmunologie an der Klinik für Allgemeine Neurologie, Universitätsklinik Münster |
| 01/2011 - 05/2013 | Fachärztin an der Klinik für Neurologie – Entzündliche Erkrankungen des Nervensystems und Neuroonkologie, Universitätsklinik Münster (Direktor: Univ.-Prof. Prof. h. c. Dr. med. H. Wiendl) |
| 2006 - 2010 | Junior group leader, Institute of Molecular Medicine and Experimental Immunology(IMMEI), University of Bonn (director: Prof. Percy Knolle) |
| 2001 - 2010 | Clinical resident, Dept. of Neurology, University Bonn (Director: Prof. Thomas Klockgether) |
| 2008 - 2009 | Clinical resident, Dept. of Psychiatry, University Bonn (Director: Prof. Wolfgang Maier) |
| 2004 - 2005 | research fellow, , Institute of Molecular Medicine and Experimental Immunology(IMMEI), University of Bonn (director: Prof. Percy Knolle) |
Functions and Memberships | |
| since 2019 | Vorstandsmitglied des Ärztlichen Beirats des DMSG-Bundesverbandes e.V. |
| since 2019 | Mitglied der DGN Kommission „Klinische Studien“ |
| since 2019 | Mitglied der DGN Kommission „Neuroimmunologie“ |
| since 2011 | Deutsche Gesellschaft für Neurologie |
| since 2008 | Deutsche Gesellschaft für Immunologie |
Appointments | |
| 2019 | Offer to a Professorship for Neuroimmunologie, (rejected) |
Publications
Lu, I; Heming, M; Cheung, P; Thomas, C; Dag, M; Giglio, G; Schroeter, C; Nelke, C; Wirth, T; König, S; Siveke, J; Klotz, L; Leo, M; Wiendl, H; Hagenacker, T; Meyer zu Hörste, G (2024) In: Nature Communications, 15 Type of Publication: Research article (journal) | |
Passlick, Johanna; Fleck, Ann-Katrin; Lauks, Sarah; Eveslage, Maria; Bergh, Florian Then; Kuempfel, Tania; Bittner, Stefan; Zipp, Frauke; Wiendl, Heinz; Klotz, Luisa (2024) In: Multiple Sclerosis, 29 Type of Publication: Research article (journal) | |
Lutfullin I, Eveslage M, Bittner S, Antony G, Flaskamp M, Luessi F, Salmen A, Gisevius B, Klotz L, Korsukewitz C, Berthele A, Groppa S, Then Bergh F, Wildemann B, Bayas A, Tumani H, Meuth SG, Trebst C, Zettl UK, Paul F, Heesen C, Kuempfel T, Gold R, Hemmer B, Zipp F, Wiendl H, Lünemann JD, German Competence Network Multiple Sclerosis (KKNMS) (2023) In: Journal of Neurology, Neurosurgery and Psychiatry, 94(1) Type of Publication: Research article (journal) | |
Engel, S.; Klotz, L.; Wirth, T.; Fleck, A.K.; Pickert, G.; Eschborn, M.; Kreuzburg, S.; Curella, V.; Bittner, S.; Zipp, F.; Schuppan, D.; Luessi, F. (2023) In: Therapeutic Advances in Neurological Disorders, 16 Type of Publication: Research article (journal) | |
Patnana P.K.; Liu L.; Frank D.; Nimmagadda S.; Behrens M.; Ahmed H.; Xie X.; Liebmann M.; Wei L.; Gerdemann A.; Thivakaran A.; Humpf H.U.; Klotz L.; Dugas M.; Varghese J.; Trajkovic-Arsic M.; Siveke J.T.; Hanenberg H.; Opalka B.; Dührsen U.; Reinhardt H.C.; Guenther U.; von Bubnoff N.; Khandanpour C. (2023) In: British Journal of Haematology, 202(5) Type of Publication: Research article (journal) |
Projects
Duration: 01/10/2023 - 30/09/2026 | 2nd Funding period Funded by: DFG - Clinical Research Unit Type of project: Subproject in DFG-joint project hosted at University of Münster | |
CRC TRR 332: Neutrophils - origin, fate & function (SFB TRR 332) Duration: 01/07/2022 - 30/06/2026 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster | |
Duration: 01/01/2021 - 30/06/2024 | 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster | |
Duration: 01/01/2021 - 30/06/2024 | 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster | |
Duration: 01/07/2020 - 30/06/2024 | 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Prizes
| Heinrich Pette Award Awarded by: German Society of Neurology Award given to: Klotz, Luisa Announced at: 25/09/2019 | Date of awarding: 15/09/2019 Type of distinction: Research award or other distinction | |
| Sobek Nachwuchspreis Awarded by: Roman, Marga und Mareille Sobek Stiftung Award given to: Klotz, Luisa Hildegard Date of awarding: 15/11/2012 Type of distinction: Research award or other distinction | |
| Oppenheim award for Multiple Sclerosis 2012 (1. Prize) Awarded by: Novartis Pharma GmbH Award given to: Klotz, Luisa Hildegard; Hucke, Stephanie Announced at: 01/01/2012 | Date of awarding: 01/01/2012 Type of distinction: Research award or other distinction | |
| BONFOR Symposium Award Awarded by: BONFOR (university hospital Bonn, Germany) Award given to: Klotz, Luisa Hildegard Date of awarding: 01/01/2005 Type of distinction: Research award or other distinction |
Doctorates
| Peripheral Immune Cell Signatures in Multiple Sclerosis Candidate: Janoschka, Claudia | Supervisors: Klotz, Luisa; Weber, Wolf-Michael Period of time: until 11/12/2020 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Influence of a dietary supplement with conjugated linoleic acid on systemic immune responses in patients with multiple sclerosis Candidate: Teipel, Jan Flavio | Supervisors: Klotz, Luisa; Period of time: until 16/11/2020 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Untersuchung MS-bedingter Einflussfaktoren auf die periphere Immunsignatur anhand von für MS diskordanten monozygoten Zwillingen Candidate: Mannig, Bianca | Supervisors: Klotz, Luisa; Kuhlmann, Tanja Period of time: until 09/11/2020 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| In vitro-Einfluss von aktivierten Makrophagen und Mikroglia auf die Migration und Proliferation von Oligodendrozytenvorläuferzellen Candidate: André Schramm | Supervisors: Klotz, Luisa; Kuhlmann, Tanja Period of time: until 04/05/2020 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Immune cell profiling during switching from Natalizumab to Fingolimod reveals differential effects on systemic immune-regulatory networks and on trafficking of… Candidate: Lohmann; Lisa | Supervisors: Klotz, Luisa; Vogl, Thomas Period of time: until 17/03/2020 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster |