Professor Dr. Joachim Jose

Current affiliations

  • Professur für Pharmazeutische Chemie (Prof. Jose)
  • Center of Interdisciplinary Sustainability Research (ZIN)

Curriculum Vitae (CV)

  • Assay development and inhibitor testing
  • Whole cell biocatalysts for synthesis of drugs and building blocks
  • Directed evolution of enzyme inhibitors and biocatalysts
  • Biosensor development and diagnostic tools

Academic Education

2003Habilitation and venia legendi in Pharmaceutical and Medicinal Chemistry.
1994Thesis, “Structure and reaction mechanism of urease from St. xylosus”, Promotion to a Dr. rer. nat.
1989Diploma in Biology (main subjects: microbiology, genetics, biochemistry) at the University of Saarbrücken and research assistant in the Department of Microbiology.

Work Experience

since 2011Full Professor (W3) and Chair for Pharmaceutical and Medicinal Chemistry at Westfälische Wilhelms-University, Münster
2008 - 2011Head of the Institute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University, Düsseldorf
2008Co-founder of the Start-up Company Autodisplay Biotech GmbH, for biocatalytic synthesis and evolutive drug design. http://www.autodisplay-biotech.com
2004 - 2008Associate Professor (C3) in Bioanalytics at the Institute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University, Düsseldorf
1998 - 2004Assistant Professor (C1) at Saarland University, Saarbrücken
2000Co-founder of the Start-up company Pharmacelcus GmbH, CRO Drug Absorption Screening. http://www.pharmacelsus.com Founding member of the center for Bioinformatics (ZBI), member of the ZBI council (2000–2005). http://www.zbi.uni-saarland.de/
1997 - 1998Senior Researcher in the group of Prof. Rolf W. Hartmann in the Department of Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken
1994 - 1997Post-Doc in the group of Prof. Thomas F. Meyer at the Max-Planck-Institute for Biology, Tübingen, Department of Infection Biology, and at the MPI for Infection Biology, Berlin, Department Molecular Genetics.

Functions and Memberships

Gesellschaft für Biochemie und Molekularbiologie (GBM, previously GBCH) Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM) Deutsche Pharmazeutische Gesellschaft (DPhG) Gesellschaft für Chemische Technik und Biotechnologie (DECHEMA) American Society for Microbiology (ASM)

Publications

Gercke, D; Lenz, F; Jose, J (2024)
In: Enzyme and Microbial Technology, 174
Type of Publication: Research article (journal)
Saenger, T; Schulte, MF; Vordenbäumen, S; Herrmann, FC; Bertelsbeck, J; Meier, K; Bleck, E; Schneider, M; Jose, J (2024)
In: International Journal of Molecular Sciences, 25
Type of Publication: Research article (journal)
Sung, JS; Kim, S; Jung, J; Kim, T-H; Kwon, S; Bae, HE; Kang, M-J; Jose, J; Lee, M; Pyun, J-C (2024)
In: ACS Pharmacology and Translational Science, 7
Type of Publication: Research article (journal)
Bong, J-H; Dombovski, A; Birus, R; Cho, S; Lee, M; Pyun, J-C; Jose, J (2024)
In: Journal of Colloid and Interface Science, 663
Type of Publication: Research article (journal)
Sung, JS; Han, Y; Yun, TG; Jung, J; Kim, T-H; Piccinini, F; Kang, M-J; Jose, J; Lee, M; Pyun, J-C (2024)
In: International Journal of Biological Macromolecules, 265
Type of Publication: Research article (journal)
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Projects

Duration: 01/04/2024 - 30/09/2028 | 2nd Funding period
Funded by: DFG - Research Training Group
Type of project: Main DFG-project hosted at University of Münster
Duration: 01/10/2020 - 31/12/2021
Funded by: Uni Münster-internal funding - Topical Programs
Type of project: Internally at the University of Münster funded project
Duration: 01/10/2020 - 31/12/2021
Funded by: Uni Münster-internal funding - Topical Programs
Type of project: Internally at the University of Münster funded project
Duration: 01/10/2019 - 31/03/2024 | 1st Funding period
Funded by: DFG - Research Training Group
Type of project: Main DFG-project hosted at University of Münster
Duration: 01/08/2018 - 31/01/2022
Funded by: Federal Ministry of Education and Research
Type of project: Participation in BMBF-joint project
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Talks

METHODS TO MEASURE PROTEIN-PROTEIN INTERACTIONS AND DISCOVERY OF POTENT INHIBITORS
Prof. Dr. Joachim Jose (12/07/2018)
2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018, Lille, France
Type of talk: scientific talk

Prizes

Best presentation award
Awarded by: 1st International Electronic Conference on Medicinal Chemistry
Award given to: Nienberg, Christian; Retterath, Anika; Becher, Kira-Sophie; Mootz, Henning; Jose, Joachim
Date of awarding: 15/11/2015
Type of distinction: Best presentation award
Best Flash Presentation Prize of TTMC 2015
Awarded by: 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015
Award given to: Jakobs, Anke; Uttarkar S; Jose, Joachim; Müller-Tidow, C; Schmidt, TJ; Klempnauer, Karl-Heinz
Date of awarding: 15/08/2015
Type of distinction: Best presentation award
Poster prize
Awarded by: Forschung der Chemischen Industrie (Symposium)
Award given to: Quehl, Paul: Riemer, Joel; Jose, Joachim
Date of awarding: 15/05/2015
Type of distinction: Best publication award
Poster prize
Awarded by: European Congress of Biotechnology
Award given to: Schüürmann, Jan; Jose, Joachim
Date of awarding: 15/07/2014
Type of distinction: Best publication award
Medaille der Fakultät für Biologie und Pharmazie der Universität Claude Bernard, Lyon
Awarded by: Universität Claude Bernard, Lyon
Award given to: Jose, Joachim
Date of awarding: 01/01/2013
Type of distinction: Research award or other distinction
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Doctorates

Buxus-Alkaloids as active compounds against pathogens causing tropical infectious diseases (Thesis written in German)
Candidate: Lara Ute Szabó | Supervisors: Schmidt, Thomas J. (Professur für Pharmazeutische Biologie und Phytochemie (Prof. Schmidt)) Jose, Joachim – Professur für Pharmazeutische Chemie (Prof. Jose) | Reviewers: Schmidt, Thomas J. (Professur für Pharmazeutische Biologie und Phytochemie (Prof. Schmidt)) Jose, Joachim – Professur für Pharmazeutische Chemie (Prof. Jose)
Period of time: 01/03/2019 - 28/02/2022
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchung zellulärer Effekte und pharmakokinetischer Eigenschaften von Inhibitoren der humanen Proteinkinase CK2
Candidate: Robin Birus | Supervisors: Jose, Joachim; Götz, Claudia; Hempel, Georg
Period of time: until 03/12/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchungen zum Einfluss posttranslationaler Modifikationen von humanem αS1-Casein auf dessen Struktur und zelluläre Funktion
Candidate: Schulte, Marten | Supervisors: Jose, Joachim; Schneider, Matthias; Lehr; Matthias
Period of time: until 17/11/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Entwicklung und Synthese eines artifiziellen β-Glucosidase-Substrates zur kovalenten Markierung β-Glucosidase-positiver Bakterienzellen
Candidate: Mönninger, Alexander | Supervisors: Jose, Joachim; Wünsch, Bernhard; Schmidt, Thomas
Period of time: until 20/05/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Nanopartikuläre DNA-Trägersysteme als alternative nicht-virale Gen-Vektoren
Candidate: Neufeld, Nelly | Supervisors: Langer, Prof. Dr. Klaus
Period of time: 01/05/2016 - 16/10/2020
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
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