The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition.

Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023)
In: Journal of Biological Chemistry, 404(4)
Type of Publication: Research article (journal)

Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis

Rohrbeck M; Hoerr V; Piccini I; Greber B; Schulte JS; Hubner SS; Jeworutzki E; Theiss C; Matschke V; Stypmann J; Unger A; Ho HT; Disse P; Strutz-Seebohm N; Faber C; Muller FU; Ludwig S; Rescher U; Linke WA; Klingel K; Busch K; Peischard S; Seebohm G (2023)
In: Cells, 12(4)
Type of Publication: Research article (journal)

Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system.

Peischard S; Möller M; Disse P; Ho HT; Verkerk AO; Strutz-Seebohm N; Budde T; Meuth SG; Schweizer PA; Morris S; Mücher L; Eisner V; Thomas D; Klingel K; Busch K; Seebohm G (2022)
In: Cellular and Molecular Life Sciences, 79(8)
Type of Publication: Research article (journal)

A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors

Schreiber, Julian A.; Schepmann, Dirk; Frehland, Bastian; Thum, Simone; Datunashvili, Maia; Budde, Thomas; Hollmann, Michael; Strutz-Seebohm, Nathalie; Wünsch, Bernhard; Seebohm, Guiscard (2019)
In: Communications biology, 2
Type of Publication: Research article (journal)

Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201

Müller S., Schreiber J., Schepmann D., Strutz-Seebohm N., Seebohm G., Wünsch B. (2017)
In: European Journal of Medicinal Chemistry, 129(null)
Type of Publication: Research article (journal)

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Pharmacological Potential of 3-Benzazepines in NMDAR-Linked Pathophysiological Processes Ritter, Nadine; Disse, Paul; Wünsch, Bernhard; Seebohm, Guiscard; Strutz-Seebohm, Nathalie (2023) In: Biomedicines, 11(5) Type of Publication: Research article (journal)
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition. Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023) In: Journal of Biological Chemistry, 404(4) Type of Publication: Research article (journal)
Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix… Disse, Paul; Aymanns, Isabel; Muecher, Lena; Sandmann, Sarah; Varghese, Julian; Ritter, Nadine; Strutz-Seebohm, Nathalie; Seebohm, Guiscard; Peischard, Stefan (2023) In: International Journal of Molecular Sciences (IJMS), 24(17) Type of Publication: Research article (journal)
Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis Rohrbeck M; Hoerr V; Piccini I; Greber B; Schulte JS; Hubner SS; Jeworutzki E; Theiss C; Matschke V; Stypmann J; Unger A; Ho HT; Disse P; Strutz-Seebohm N; Faber C; Muller FU; Ludwig S; Rescher U; Linke WA; Klingel K; Busch K; Peischard S; Seebohm G (2023) In: Cells, 12(4) Type of Publication: Research article (journal)
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives Ritter N; Disse P; Aymanns I; Mücher L; Schreiber JA; Brenker C; Strünker T; Schepmann D; Budde T; Strutz-Seebohm N; Ametamey SM; Wünsch B; Seebohm G (2023) In: Molecular Neurobiology, 60(12) Type of Publication: Research article (journal)
Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Peischard S; Möller M; Disse P; Ho HT; Verkerk AO; Strutz-Seebohm N; Budde T; Meuth SG; Schweizer PA; Morris S; Mücher L; Eisner V; Thomas D; Klingel K; Busch K; Seebohm G (2022) In: Cellular and Molecular Life Sciences, 79(8) Type of Publication: Research article (journal)
4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region Bollmann, Eva; Schreiber, Julian Alexander; Ritter, Nadine; Peischard, Stefan; Ho, Huyen Tran; Wünsch, Bernhard; Strünker, Timo; Meuth, Sven; Budde, Thomas; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2020) In: Cellular physiology and biochemistry, 54(2) Type of Publication: Research article (journal)
A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors Schreiber, Julian A.; Schepmann, Dirk; Frehland, Bastian; Thum, Simone; Datunashvili, Maia; Budde, Thomas; Hollmann, Michael; Strutz-Seebohm, Nathalie; Wünsch, Bernhard; Seebohm, Guiscard (2019) In: Communications biology, 2 Type of Publication: Research article (journal)
An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis Amedonu, Elsie; Brenker, Christoph; Barman, Sumanta; Schreiber, Julian A; Becker, Sebastian; Peischard, Stefan; Strutz-Seebohm, Nathalie; Strippel, Christine; Dik, Andre; Hartung, Hans-Peter; Budde, Thomas; Wiendl, Heinz; Strünker, Timo; Wünsch, Bernhard; Goebels, Norbert; Meuth, Sven G; Seebohm, Guiscard; Melzer, Nico (2019) In: Frontiers in Neurology, 10 Type of Publication: Research article (journal)
Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201 Müller S., Schreiber J., Schepmann D., Strutz-Seebohm N., Seebohm G., Wünsch B. (2017) In: European Journal of Medicinal Chemistry, 129(null) Type of Publication: Research article (journal)